临床与病理杂志Issue(6)：1199-1204,6.DOI:10.3978/j.issn.2095-6959.2015.06.063
输尿管小细胞癌1例及文献复习
Small cell carcinoma of the ureter：a case report and literature review
张冬梅 1魏建国2
作者信息
- 1. 北京市宣武中医医院病理科，北京 100050
- 2. 浙江省绍兴市人民医院病理科，浙江 绍兴 312000
- 折叠
摘要
Abstract
Objective:To explore the clinicopathologic feature and differential diagnosis of small cell carcinoma (SCC) of the ureter.Methods:The clinical, histopathological and immunohistochemical features of one case of SCC of the ureter were analyzed and the literatures were reviewed.Results: A 70-year-old female presented with a left flank pain 22 days. CT showed the left ureter expansion, and the lower ureter slightly hyperattenuation. hTe imaging diagnosis did not exclude the possibility of ureteral tumors. Intraoperative frozen section analysis suggested small round cell tumor. The patient underwent left nephroureterectomy. Pathological examination showed that the tumor tissue consisted of small, round or oval shaped cells, with a prominent nucleus, scant cytoplasm and granular chromatin. A high mitotic index may be observed. Tumor cells expressing Syn, ChA and NSE in immunohistochemical staining.Conclusion: SCC of ureter is a relatively rare malignant tumor with high invasiveness and poor prognosis. hTe pathological diagnosis depends on pathological and immunohistochemicalexamination. Neuroendocrine markers positive is one of the important reference. The differential diagnoses included poorly differentiated UC, plasmacytoid carcinoma, malignant lymphoma, lymphoepithelioma like carcinoma, or primitive neuroectodermal tumor. The multimodal therapy of these tumors included surgery, chemotherapy and radiation.关键词
小细胞癌/输尿管/免疫组织化学Key words
small cell carcinoma (SCC)/ureter/immunohistochemistry引用本文复制引用
张冬梅,魏建国..输尿管小细胞癌1例及文献复习[J].临床与病理杂志,2015,(6):1199-1204,6.
