神经损伤与功能重建Issue(3):209-213,5.DOI:10.3870/sjsscj.2014.03.011
iScore、PLAN 和 ASTRAL 评分对急性缺血性卒中患者不良结局风险预测价值探讨
External Validation of the iScore, PLAN Score and ASTRAL Score to Predict Functional Out-comes for Acute Ischemic Stroke
金迪 1陈忠云 1李婧 1李珊珊 1徐志伟 1杜继臣 1杨旭1
作者信息
- 1. 北京大学航天临床医学院神经内科北京 100049
- 折叠
摘要
Abstract
ObjectiveTo validate the significance of iScore, PLAN score and ASTRAL score in predicting the outcome of Chinese patients at 3 month after acute ischemic cerebral stroke (AIS). Methods: From December 2012 to August 2013, 221 AIS patients who hospitalized in neurology department of our hospital were collected prospectively. Related baseline data were recorded and calculated by iScore, PLAN score and ASTRAL score. The outcome events were defined as death and poor functional outcome, or modified Rankin Scale (≥3). Model discrimination was quantified by calculating the area under the Receiver Operating Characteristic curve (AUC), and calibration was assessed by goodness of fit test and correlation coefficient. Results: Seventy-one cases (32.1%) had 3-month an unfavorable outcome. AUC for iScore, PLAN score and ASTRAL score were 0.816, 0.830 and 0.841 respectively.x2 of were 1.676, 5.976 and 12.858 (all >0.05), and correlation coefficient were 0.899, 0.857 and 0.939 (all <0.05), respectively. Conclu-sion: All the three scales can predict 3-month functional outcomes in Chinese stroke patients precisely and reliably. There was a high correlation between observed and expected probability of unfavorable outcome.关键词
缺血性卒中/预后/量表/受试者工作特征曲线Key words
acute ischemic stroke/prognosis/score/Receiver Operating Characteristic curve分类
医药卫生引用本文复制引用
金迪,陈忠云,李婧,李珊珊,徐志伟,杜继臣,杨旭..iScore、PLAN 和 ASTRAL 评分对急性缺血性卒中患者不良结局风险预测价值探讨[J].神经损伤与功能重建,2014,(3):209-213,5.