神经损伤与功能重建Issue(3)：216-219,4.DOI:10.3870/sjsscj.2015.03.010
高压氧联合甲钴胺治疗2型糖尿病周围神经病电生理疗效观察
Electrophysiological Changes after Hyperbaric Oxygen Combined with Mecobalamin in the Treatment of Type 2 Diabetes Peripheral Neuropathy
摘要
Abstract
Objective: To investigate the electrophysiological changes after of treatment of hyperbaric oxygen (HBO) combined with mecobalamin in patients with type 2 diabetic peripheral neuropathy (DPN). Methods: Six-ty-nine cases of patients with DPN were randomly divided into control group (n=36) and treatment group (n=33). Cases in the control group were given mecobalamin treatment, and those in the treatment group were given both mecobalamin and HBO treatment. The electrophysiological examination was performed before and after the treat-ment. Result: In the treatment group, the median nerve, ulnar nerve, ulnar nerve, sural nerve, common peroneal nerve and tibial nerve sensory nerve conduction velocity (SCV), sensory nerve action potential (SNAP) amplitude and compound muscle action potential (CMAP) amplitude were higher than those before treatment (P<0.05), and CMAP latency was shorter than that before treatment (P<0.05). In the control group, the median nerve and ulnar nerve SCV were higher than those before treatment (P<0.05). The median nerve and ulnar nerve SCV in the treat-ment group were higher than those in the control group after treatment (P<0.05). Conclusion: HBO combined with Methylcobalamin is effective to treat DPN.关键词
2 型糖尿病/周围神经病/甲钴胺/高压氧Key words
type 2 diabetes/peripheral neuropathy/mecobalamin/hyperbaric oxygen分类
医药卫生引用本文复制引用
孙太欣,周丽丽,孙晨曦,周国平,李丹..高压氧联合甲钴胺治疗2型糖尿病周围神经病电生理疗效观察[J].神经损伤与功能重建,2015,(3):216-219,4.基金项目
国家电网公司科学技术项目 （）
