摘要
Abstract
Objective:To investigate the related factors of intracranial infections in brain-injured patients who re-ceived invasive intracranial pressure monitoring after craniotomy. Methods: A retrospective analysis of the clinical data was conducted involving 56 brain-injured patients who received invasive intracranial pressure monitoring be-tween June, 2013 and June, 2014. The factors including age, gender, Glasgow coma scale (GCS) score at admis-sion, incision type, duration of the operation, number of operations, duration of incision drainage tube, sensor inser-tion site, duration of the sensor, glucose and cerebrospinal fluid leak were compared between the patients with in-tracranial infections (infection group) and ones without infections (non-infection group). All data were analyzed with univariate analysis and multivariate Logistic regression to identify the related factors and independent risk fac-tors associated with intracranial infections. Results: Incision type (x2=4.058, P=0.044), sensor insertion site (x2=5.486, P=0.019), cerebrospinal fluid leak (x2=12.562, P<0.001), duration of incision drainage tube (t=2.71, P=0.009), duration of the sensor (t=2.74, P=0.01) and duration of the operation (t=2.06, P=0.045) were relevant fac-tors of intracranial infections. Duration of incision drainage tube (OR=0.347, P=0.009), duration of the sensor (OR=0.640, P=0.048) and cerebrospinal fluid leak (OR=14.243, P=0.005) were the independent risk factors for the intracranial infections. Conclusion: There are a variety of factors related to intracranial infections in brain-injured patients with placement of intracranial pressure monitoring. Prolonged duration of incision drainage tube, pro-longed duration of the sensor and cerebrospinal fluid leak were the independent risk factors for the intracranial in-fections.关键词
颅内压监测/颅内感染/颅脑外伤/多因素分析Key words
intracranial pressure monitoring/intracranial infection/traumatic brain injury/multi-factor analysis分类
医药卫生
