广西科学Issue(2)：130-134,5.
毛郁金乙醇提取物降血脂作用研究
Antihyperliposis Effects of Ethanol Extract from Curcu-maaromatica
摘要
Abstract
Objective]The antihyperliposis function of the ethanol extract from Curcuma aromatica was studied on rats in order to provide the basis for its comprehensive development and utilization.[Methods]High lip-id rat model was prepared by feeding a high-fat diet and gastric perfusion of intralipid,then de-livered with different doses of the ethanol ex-tract from Curcuma aromatica .All experimen-tal rats were divided into 6 groups:A normal control group,a high lipid model group,a posi-tive group(Simvastatin)and three groups of eth-anol extract from Curcuma aromatica with the equivalent weight of 1 8 g crude drug · kg-1 · d-1 ,1 2 g crude drug · kg-1 · d-1 and 6 g crude drug·kg-1 · d-1 ,respectively.[Results]The ethanol extract from Curcuma aromatica could decrease the value of total cholesterol(CHOL),triglyceride (TG)and the low density lipopro-tein-cholesterol (LDL-C)in the blood of rats,and also increase the value of high density lipo-protein-cholesterol (HDL-C).The CHOL and LDL-C decreasing effects ranked as:high>mid-dle>low dose group.The middle dose group has a better effect on TG decreasing and HDL-C increasing.All the dose groups of Curcuma aromatica have significantly lower levels of LDL-C (P<0.01).[Conclusion]The ethanol extract from Curcuma aromatica shows clear effects on antihyperliposis.关键词
毛郁金/乙醇提取物/大鼠/降血脂Key words
Curcuma aromatica/ethanol extract/rat/antihyperliposis分类
医药卫生引用本文复制引用
吴尤娇,黄敏桃,黄云峰,赖茂祥,黄庶识,刘华钢..毛郁金乙醇提取物降血脂作用研究[J].广西科学,2015,(2):130-134,5.基金项目
国家科技支撑计划项目(2011BAI01B04),广西科学研究与技术开发计划项目(0992003A-20)和广西自然科学基金项目(2010GXNSFD013044)资助。 （2011BAI01B04）
