摘要
Abstract
Objective To investigate the coagulation,D-dimer and blood lipid levels in patients with progressive cerebral infarction and their clinical significance .Methods Ninety-four patients with cerebral infarction were divided into progressive cerebral infraction group(43 cases) and completely cerebral infraction group(51 cases) according to the treatment course,and 45 healthy cases in the same period were selected as control group.Enzyme-linked immunosorbent assay(ELISA) was used to detect prothrombin time(PT),thrombin time (TT),activated partial thromboplastin time(APTT) and fibrinogen (Fib).The D-dimer level was detected by colloidal gold method .The levels of TC,TG,HDL-C and LDL-C were tested by Architect automatic biochemistry analyzer .Results The levels of PT,TT and APTT in the progressive cerebral infraction group were significantly lower than those in the completely cerebral infraction group and control group (P<0.05),the levels of Fib and D-dimer were significantly higher than those in the completely cerebral infraction group and control group (P<0.05).There was no significant difference in the levels of PT ,TT,APTT,Fib and D-dimer between completely cerebral infraction group and control group ( P >0.05 ) .The levels of TC , TG and LDL-C in the progressive cerebral infraction group were higher than those in the completely cerebral infraction group and control group (P<0.05),while the HDL-C level showed no statistically significant difference in contrast with that in the completely cerebral infarction group or control group (P>0.05).The levels of TC,TG and LDL-C in the completely cerebral infarction group were higher than those in the control group (P<0.05),while the HDL-C level showed no statistically significant difference in contrast with that in the control group ( P>0 .05 ) .Conclusion The dynamic changes in the coagulation ,D-dimer and blood lipid levels are closely associated with the severity of the disease , and it is valuable in the assessment of the prognosis of progressive cerebral infarction .关键词
脑梗死/凝血功能/D-二聚体/血脂Key words
Cerebral infarction/Coagulation/D-dimer/Blood lipid分类
医药卫生
