广西医学Issue(8):1031-1033,3.DOI:10.11675/j.issn.0253-4304.2014.08.03
鼻咽癌组织微电流、表皮生长因子受体与鼻咽癌分化的关系
Relationship between Micro-Current,Epidermal Growth Factor Receptor and Differentiation in Nasopharyngeal Carcinoma
摘要
Abstract
Objective To explore the change of micro-current and the expression of epidermal growth factor receptor( EGFR) in nasopharyngeal carcinoma tissues ,and to investigate the significance of micro-current and EGFR for the differentiation of nasopharyngeal carcinoma .Methods The micro-current detector and immunohistochemistry were used to detect micro-current and EGFR level in 37 cases of nasopharyngeal carcinoma tissues and 15 cases of nasopharyngeal mucosae with chronic inflammation.Results The positive rates of micro-current and EGFR in nasopharyngeal carcinomas group were 70 .3% and 13 .3%, respectively , which were higher than those in nasopharyngeal mucosae with chronic inflammation group ( P<0 .05 ) .The positive rate of EGFR in nasopharyngeal carcinoma patients with lymphatic metastasis was significantly higher than that without metastasis ( P<0 .05 ) .Conclusion The detection of micro-current contributes to the verification of the nasopharyngeal carcinoma tissues and non -nasopharyngeal carcinoma tissues.Micro-current and EGFR don′t correlate with the differentiation of nasopharyngeal carcinoma .关键词
鼻咽癌/微电流/表皮生长因子受体Key words
Nasopharyngeal carcinoma/Micro-current/Epidermal growth factor receptor分类
医药卫生引用本文复制引用
彭忠异,阮萍,李筱,梁海萍,张锡流..鼻咽癌组织微电流、表皮生长因子受体与鼻咽癌分化的关系[J].广西医学,2014,(8):1031-1033,3.基金项目
广西科学研究与技术开发计划项目 ()