工业技术创新Issue(2)：192-196,5.
醋酸纤维素手性固膜对R,S-扁桃酸的拆分研究
Enantiomeric separation of (R,S)-mandelic acid using cellulose acetate membrane
徐晓林1
作者信息
- 1. 曲靖师范学院化学化工学院，云南省曲靖，655011
- 折叠
摘要
Abstract
Since cellulose acetate has been widely used for membrane separations and chiral stationary phase in HPLC, It showed favorable film-forming performance and enantiomeric recognition potency. an enantioselective membrane was prepared using cellulose acetate as the membrane material. The flux and permselective properties of a membrane were studied using mandelic acid racemate as the feed solution. The top surface and cross-section morphology of the resulting membrane were examined using scanning electron microscopy. An optical resolution of at 3.9 enantiomeric separation factor was achieved when the enantioselective membrane was prepared with 30wt.%cellulose acetate, 15wt.%N, N-dimethylformamide in the casting solution of acetone, the evaporation time of 5 minutes and operating pressure of 0.2 MPa. This work indicates that the enantioselective cellulose acetate membrane could soon become very attractive for industrial uses.关键词
醋酸纤维素/膜分离技术/R,S-扁桃酸/手性拆分Key words
Cellulose acetate/The technology of membrane separation/(R,S)- Mandelic acid/Chiral separation分类
矿业与冶金引用本文复制引用
徐晓林..醋酸纤维素手性固膜对R,S-扁桃酸的拆分研究[J].工业技术创新,2014,(2):192-196,5.
