高压物理学报Issue(4)：498-506,9.DOI:10.11858/gywlxb.2014.04.017
超高压对蛋白质的影响
Effects of High Hydrostatic Pressure on Proteins
摘要
Abstract
This review introduces the effects of high hydrostatic pressure on the molecular volume,non-covalent bond and conformation of protein.The molecular volume is decreased,and the hydrogen bond,electrovalent bond,and hydrophobic interaction are influenced by compression.The secondary, tertiary and quaternary structures of protein are influenced by pressure below 800 MPa.Tertiary and quaternary structures are more pressure-sensitive than secondary structure.Pressure below 8 GPa does not influence the primary structure of proteins.关键词
超高压/蛋白质/分子体积/非共价键/结构Key words
ultra-high pressure/protein/molecular volume/non-covalent bond/conformation分类
数理科学引用本文复制引用
李仁杰,廖小军,胡小松,吴继红..超高压对蛋白质的影响[J].高压物理学报,2014,(4):498-506,9.基金项目
国家科技支撑计划（2011BAD27B02-03-02）；农业部948重点项目 （）
