解放军医药杂志Issue(5)：54-57,4.DOI:10.3969/j.issn.2095-140X.2014.05.015
通降和胃法治疗胃食管反流病临床效果的meta分析
Traditional Chinese Medicine Tongjiang Hewei Therapy in Treatment of Patients with Gastroesophageal Reflux Disease:A Meta-analysis
摘要
Abstract
Objective To compare the effects of traditional Chinese medicine and western medicine in treatment of gastroesophageal reflux disease ( GERD) using meta analysis. Methods Relevant literature published during January 1990 and February 2014 was randomly selected and evaluated. The meta analysis of efficacy and adverse reactions were performed with RevMan 5. 2 software. Results A total of 14 RCTs ( randomized clinical trial) including 1703 patients with GERD with a score of 2. 5-3. 0 Jadad points, were recruited in this study. The meta-analysis indicated that the effi-cacy of traditional Chinese medicine was significantly better than that of western medicine in treatment of GERD ( com-bined RR= 1. 17, 95% CI:1. 12-1. 22, P< 0. 01), but the difference in incidence rate of adverse reactions between traditional Chinese medicine and western medicine was not statistically significant (combined RR= 0. 24, 95% CI:0. 04-1. 52, P>0. 05). Conclusion Traditional Chinese medicine of Tongjiang Hewei therapy in treatment of GERD shows bet-ter efficacy compared with that of western medicine treatment, but the two treatments have the similar scores of safety.关键词
胃食管反流病/中医治法/中西医学比较研究/随机对照试验/meta分析Key words
Gastroesophageal reflux disease/Therapeutic method/Comparative research on traditional Chinese medicine with western medicine/Randomized controlled trial/Meta-analysis分类
医药卫生引用本文复制引用
孙成宏,陈迪,王斌..通降和胃法治疗胃食管反流病临床效果的meta分析[J].解放军医药杂志,2014,(5):54-57,4.基金项目
国家自然科学基金项目(81202858) （81202858）
现代信息科学与网络技术北京市重点实验室开放课题(XDXX1306) （XDXX1306）
