解放军医药杂志Issue(6)：17-21,5.DOI:10.3969/j.issn.2095-140X.2014.06.005
低钠血症与肺动脉高压预后的相关性研究
Correlation between Hyponatremia and Prognosis of Patients with Pulmonary Arterial Hypertension
摘要
Abstract
Objective To explore the correlation between hyponatremia and the prognosis of patients with pul-monary arterial hypertension ( PAH) . Methods Clinical data of 50 PAH patients during January 2009 and November 2011 in Wuhan Asian Heart Hospital was retrospectively analyzed. Results Compared with those in normal serum sodi-um group, the values of heart rate ( HR) , right atrial pressure ( RAP) , right atrial area index ( RAAI) , right ventricular area index ( RVAI) , tricuspid regurgitation ( TR) , ratio of right atrial diameter to left atrium diameter ( RAD/LAD) and ratio of right ventricular end-diastolic volume to left ventricular end-diastolic volume ( RVEDV/LVEDV) were significant-ly higher in hyponatremia group, while the values of stroke volume index (SVI), right ventricular stroke work index ( RVSWI) , ratio of stroke volume to pulmonary arterial systolic pressure ( SV/PP) , tricuspid annular plane systolic ex-cursion (TAPSE) and left ventricle diameter (LVD) were significantly lower (P<0. 05, P<0. 01). The one-year and two-year of survival rates in normal sodium group and hyponatremia group were 93. 33% & 83. 33% and 50. 00% &20. 00%respectively, and the fatality rate in normal sodium group was significantly higher than that in hyponatremia group (P<0. 01). Conclusion Serum sodium level is significantly associated with condition's severity and prognosis of pa-tients with pulmonary arterial hypertension, and therefore hyponatremia is an important indicator of poor prognosis in PAH patients.关键词
低钠血症/高血压,肺性/预后Key words
Hyponatremia/Hypertension, pulmonary/Prognosis分类
医药卫生引用本文复制引用
邓晓娴,周红梅,彭婷,尚小珂,周欣..低钠血症与肺动脉高压预后的相关性研究[J].解放军医药杂志,2014,(6):17-21,5.基金项目
国家十二五科技支撑项目(2011BAL11B15) （2011BAL11B15）
