解放军医药杂志Issue(9)：30-32,3.DOI:10.3969/j.issn.2095-140X.2014.09.008
载脂蛋白CⅡ、CⅢ在脑梗死患者血清中的动态变化及临床意义
Dynamic Changes and Clinical Significances of Serum Apolipoprotein C-Ⅱ and Apolipoprotein C-Ⅲ Levels in Patients with Cerebral Infarction
摘要
Abstract
Objective To observe the dynamic changes of serum apolipoprotein C-Ⅱ(ApoCⅡ)and apoli-poprotein C-Ⅲ( ApoCⅢ)levels in patients with cerebral infarction( CI)and to explore the its relationship with severe degree of the pathogenetic condition. Methods A total of 62 ACI inpatients from January to March 2007 were selected as observation group,while 30 healthy persons taking medical examinations during the same period were chosen as control group. The levels of serum ApoCII and ApoCⅢ were detected on 1st d,7th d and 14th d after stroke onset in observation group,and the results were compared with those in control group. The relationship between the levels with the score of the National Institutes of Health stroke scale(NIHSS)was also analyzed. Results The levels of ApoCⅡand ApoCⅢ on 1st d,7th d and 14th d after stroke onset in observation group were significantly higher than those in control group,and the highest levels were found on 1st d after pathogenesy,and then the levels gradually decreased with the relieved conditions ( P<0. 05). The NIHSS score on 14th d after stroke was significantly lower than those on 1st d and 7th d after stroke. The ApoCⅡor ApoCⅢ levels had significantly positive correlation with NIHSS score(r=0. 827,P<0. 001. r=0. 914,P<0. 001). Conclusion ApoCⅡand ApoCⅢ level changes may be of great importance in the observation of the ACI con-dition and judgement of the prognosis.关键词
脑梗死/载脂蛋白 CⅡ/载脂蛋白 CⅢ/NIHSS评分Key words
Brain infarction/Apolipoprotein C-II/Apolipoprotein C-Ⅲ/NIHSS score分类
医药卫生引用本文复制引用
徐玉,高瑞利,王惠凌,乔民,谷建芳,王静,高利涛,王雪笠,冯连元..载脂蛋白CⅡ、CⅢ在脑梗死患者血清中的动态变化及临床意义[J].解放军医药杂志,2014,(9):30-32,3.基金项目
河北省科技攻关计划项目 （）
