解放军医药杂志Issue(2)：89-93,5.DOI:10.3969/j.issn.2095-140X.2015.02.025
临床常规生化项目室内质控方法的设计
Indoor Quality Control Rules for Routine Clinical Biochemical Tests
郑强1
作者信息
- 1. 110044 沈阳，沈阳市骨科医院输血科
- 折叠
摘要
Abstract
Objective To study the indoor quality control rules for routine clinical biochemical tests. Methods Quality control indexes of Alkaline phosphatase (ALKP), potassium (K) and calcium (Ca) from July to December 2012 were collected. The accumulative coefficient of variation (CA) of indoor quality control was used as imprecision degree;bias was calculated using external quality assessment of Clinical Laboratory Center of Chinese Ministry of Public Health;total error al-lowance was evaluated using proficiency testing in American Clinical Laboratory Improvement Amendments 88 (CLIA'88). The feasible indoor quality control methods were made based on operational process of specification chart so as to improve the prob-ability for error detection (Ped) and reduce the probability for false rejection (Pfr). Results The measured value of each batch control number was 2, and ALKP and K were chosen for 1-3 s as quality control rule in order to achieve Ped above 90%and Pfr below 5%;however, the measured value of each batch control number was 4, and Ca was chosen for 1-3 s/2-2 s/R-4 s/4-1 s/12-X as quality control rule in order to achieve Ped above 90% and Pfr below 5%. Conclusion Different biochem-ical analysis projects should select different control rules based on the different performance characteristics of analytical methods.关键词
血液化学分析/质量控制/误差检出概率/假失控概率/操作过程规范图Key words
Blood chemical analysis/Quality control/Probability for error detection/Probability for false rejec-tion/Operational process of specifications chart分类
医药卫生引用本文复制引用
郑强..临床常规生化项目室内质控方法的设计[J].解放军医药杂志,2015,(2):89-93,5.
