河北医学Issue(10):1601-1604,4.DOI:10.3969/j.issn.1006-6233.2014.10.006
血清 IL-23联合血浆脑钠肽检测对判断慢性心力衰竭患者预后的影响
Influence of Serum IL-23 Combined with Plasma Brain Natriuretic Peptide on Judging the Prognosis of Patients with CHF
摘要
Abstract
Objective:To explore the influence of serum IL-23 combined with plasma brain natriuretic peptide on judging the prognosis indicators of patients with chronic heart failure ( CHF) .Method:51 patients with CHF treated in our hospital from May 2011 to May 2013 were selected as the clinical research object , as the experimental group .And selected 51 healthy subjects as control group in the same period .Detected the content of serum IL-23 and plasma brain natriuretic peptide in the two groups and compared the positive de-tection rate.Result:The possitive detection rate of serum IL-23 and plasma brain natriuretic peptide of ex-perimental group (96.08%,94.12%) were significantly higher than those in control group (7.84%,9.80%) (P<0.05);In experimental group (51 cases),there were 48 patients had their cardiac function improved and survived ,BNP level had positive correlation with YNHA grading , difference was significant ( p<0.05 ) , and mortality increased when BNP level increased .Conclusion:Serum IL-23 combined with plasma brain natri-uretic peptide has certain advantages in judging the prognosis of patients with CHF , which can reflect cardiac function classfication and progressive disease and more accurate ,have certain significance in evaluating path-ogenetic condition of the patients , it’ s worthy of being applied in clinic .关键词
血清IL-23/血浆脑钠肽/慢性心力衰竭/预后Key words
Serum IL-23/Plasma brain natriuretic peptide/Chronic heart failure/Prognosis引用本文复制引用
王志贵,范艺花..血清 IL-23联合血浆脑钠肽检测对判断慢性心力衰竭患者预后的影响[J].河北医学,2014,(10):1601-1604,4.基金项目
陕西省自然科学基金项目, ()