河北医学Issue(12)：1964-1968,5.DOI:10.3969/j.issn.1006-6233.2014.12.010
乙型肝炎病毒及幽门螺杆菌感染对慢性乙型肝炎患者胃粘膜病变的影响
Influence of HBV and Hleicobacter Pylori Infection for Gastric Mu cosa in Patients with Chronic Hepatitis B Virus
摘要
Abstract
Objective:To analyze the relations between hepatitis B virus markers and helicobacter pylori in patients with hepatitis B virus infection in gastric mucosa, the effect of HBV and helicobacter pylori infection on gastric mucosa in chronic hepatitis B patients .Method:Choose 60 cases patients with chronic HBV infection diagnosed by serum HBV DNA examination .HBV in serum were exterminated with ELISA , while HBsAg and HBcAg and HP-IgG in gastric mucosa were exterminated by immunohistochemistry .Uresase detection , HE, Fuchsin staining and immunohistochemical analysis of helicobacter pylori IgG antigen were conducted .Result:29 cases of gastric mucosa in 60 cases of hepatitis B virus infection in can be detected in hepa-titis B virus, of which 20 patients with gastric tissue abnormalities , inflammatory lesions in the gastric mucosa moderate , se-vere, accounting for 68.97%.31 cases of chronic hepatitis B virus infection in gastric mucosa tissue abnormalities , inflammato-ry lesions with its mild, moderate, accounting for 70.97%.The difference was statistically significant (P <0.05).The degree of chronic hepatitis B virus infection in gastric mucosa surface antigen of hepatitis B virus and hepatitis B virus core antigen -positive patients were heavier gastric lesions .Expression of gastric inflammation in patients with H .pylori infection rate was 77. 78%and 79.31%, respectively , in patients with chronic hepatitis and cirrhosis patients , Helicobacter gastritis patients without liver disease pylori infection rate was 56.70%,There's no significant difference by comparison among groups , the difference has no statistically significant (P>0.05).Conclusion: HBV can be found growing and copying in gastric mucosa , and also be found to be an important factor of gastric mucosa lesions in HBV infection patients;the damage of gastric mucosa with the infec-tion of HBV in the gastric mucosa in the HBV infection patients is of correlation;NO relationship between HBV and Helicobact-er pillories press ions was observed in gastric mucosa , there's no significant association between infection and gastric mucosal lesions in chronic hepatitis B patients of Helicobacter pylori.关键词
乙型肝炎病毒/粘膜病变/幽门螺杆菌Key words
Hepatitis B virus/Mucosal lesions/Helicobacter pylori引用本文复制引用
庞念德,陈安海..乙型肝炎病毒及幽门螺杆菌感染对慢性乙型肝炎患者胃粘膜病变的影响[J].河北医学,2014,(12):1964-1968,5.基金项目
广东省深圳市盐田区科技计划资助项目， （）
