河北医学Issue(1)：55-58,4.DOI:10.3969/j.issn.1006-6233.2015.01.018
血清 sTWEAK 与冠心病严重程度的关系及其对急性心肌梗死发病的预测价值
Relationship of the Serum sTWEAK with Severity CHD and its Predictive Value for AMI
摘要
Abstract
Objective:To investigate the relationship between human soluble tumor necrosis factor-like apoptosis weak inducible factor ( sTWEAK ) with severity of coronary heart disease and its predictive value for acute myocardial infarction ( AMI). Method:176 cases with CHD in our hospital, including 98 patients with unstable angina pectoris ( UAP group ), 18 patients with stable angina pectoris ( SAP group ), 60 pa-tients with acute myocardial infarction ( AMI group ) and 36 cases in normal control group. The sTWEAK concentration was measured by sTWEAK ELISA and the assessment of the severity of CHD were used by cor -onary angiography Gensini score method. Result:sTWEAK concentration of 60 patients with AMI were sig-nificantly higher than the other patients, the difference was statistically significant ( P<0.05); the clinical actual concentration of sTWEAK had positively correlated with Gensini scores, and it can be regarded as one of the factors for high-risk of AMI, the difference was statistically significant (P<0.05).Conclusion: For the patients with acute myocardial infarction, the serum sTWEAK concentration level is higher than the non-AMI patients and the control group patients, Therefore, sTWEAK is regarded as a risk factor for the onset of AMI and its positive correlation with CHD severity.关键词
血清sTWEAK/冠心病/急性心肌梗死Key words
Serum sTWEAK/Coronary heart disease/Acute myocardial infarction引用本文复制引用
段霄燕,余建中,陈丽..血清 sTWEAK 与冠心病严重程度的关系及其对急性心肌梗死发病的预测价值[J].河北医学,2015,(1):55-58,4.基金项目
四川省医学会课题， （）
