河北医学Issue(2)：339-343,5.DOI:10.3969/j.issn.1006-6233.2015.02.057
2012年至2014年注射用中成药引发不良反应调查分析∗
Survey of Adverse Drug Reaction Induced by Chinese Herb Injection from 2012 to 2014
摘要
Abstract
Objective:To investigate clinical characteristics and influencing factors of adverse drug re-actions induced by Chinese herb injections, to provide a reference for the rational use of chinese herb. Meth-od:Counted ADR incidence of 2042 patients treated with Chinese herb injections during Jan. 2012 to Jun. 201, and analyzed clinical features of ADR, applied nested case-control design and analysed risk factors for ADR. Result:53 cases occurred ADR, the rate was 2.60%;ADR induced by different Chinese herb was not not statistically significant (P>0.05);ADR patients less than year-old children, accounting for 33.96 %;occurred in the post-infusion 1 day, accounting for 73.59%;involving organ damage and skin damage to the digestive system, accounting for 30.19%, 26.42% respectively;Logistic regression analysis showed that drip too fast ( OR = 0.83, P <0.05 ) , solvent misuse ( OR = 0.52, P <0.05) were independent risk factors for ADR occurred, before the injection without red tube ( OR = 0.28, P <0.05) were protective factors ADR occurred. Conclusion:Different types of injectable medicine can lead to ADR, It should pay attention to a reasonable adjustment and selection of suitable solvent injection drip, before the injection of strict red tube, ensure drug safety.关键词
中成药/注射剂/不良反应Key words
Chinese herb/Injection/Adverse reactions引用本文复制引用
郭惠萍,李雪敏..2012年至2014年注射用中成药引发不良反应调查分析∗[J].河北医学,2015,(2):339-343,5.基金项目
2011年四川省卫生厅科研课题,(编号:110023) （编号:110023）
