河北医学Issue(3)：509-511,3.DOI:10.3969/j.issn.1006-6233.2015.03.055
超敏 C 反应蛋白联合 D－二聚体检测在冠心病早期诊断的临床意义
The Diagnosis Significance of Assays of hs-CRP and D-dimeride in Early Diagnosis of CAD
摘要
Abstract
Objective:To investigate the clinical significances of assays of serum hypersensitive C reac-tion protein ( hs-CRP ) and plasma D-dimeride ( D-D ) in early diagnosis of coronary artery disease ( CAD) .Method:A total of 100 patients with CAD were selected and divided into coronary artery disease group, including 29 patients with acute myocardial infarction ( AMI) , 38 patients with unstable angina pec-toris ( UAP ) and 33 patients with stable angina pectoris ( SAP );and 30 people with normal health examina-tion results in the same period were selected and divided into control group .The serum hs-CRP and plasma D-D of the two groups were assayed .Result: The CAD group had higher serum hs-CRP and plasma D-D level than those in the control group , and the differences were statistically significant (P<0.05).The AMI group had the highest serum hs-CRP and plasma D-D, the SAP group had the lowest serum hs-CRP and plasma D-D, the UAP group was in the middle , and the differences were statistically significant ( P<0.05) . The serum hs-CRP (r =0.763, P<0.05) level and plasma D-D (r =0.647, P<0.05) level were signifi-cantly directly correlated with CAD degree .Conclusion:The serum hs-CRP level and plasma D-D level are significantly increased in patients with CAD , the levels are directly correlated with the disease degree , and consequently has important clinical significances in early diagnosis and clinical typing of CAD .关键词
冠心病/超敏C反应蛋白/D-二聚体Key words
Coronary artery disease/Hypersensitive C reaction protein/D-dimeride引用本文复制引用
刘正群,付林..超敏 C 反应蛋白联合 D－二聚体检测在冠心病早期诊断的临床意义[J].河北医学,2015,(3):509-511,3.基金项目
四川省科技厅资助项目， （）
