河北医学Issue(8)：1419-1423,5.DOI:10.3969/j.issn.1006-6233.2015.08.017
多巴胺与去甲肾上腺素在休克治疗中的应用研究
Application of Dopamine and Norepinephrine in Shock Therapy
摘要
Abstract
Objective:To investigate dopamine and norepinephrine in shock therapy.Method:A total of 200 shock patients were collected.According to the method of treatment, they were divided into dopamine ( DA) group ( n =65) , norepinephrine ( NE) group ( n =65) , dopamine and norepinephrine ( DA+NE) group (n =70).Treatment efficacy, incidence of complications and 28 days mortality were compared be-tween groups.Result: After treatment, serum creatinine levels in three groups were significantly different. Serum creatinine levels in DA group were significantly higher than the NE group and DA +NE group.Other indicators had no statistical difference.Arrhythmia was 30.76%in the DA group, which was significantly higher than 13.85%in the NE group (χ2=5.370, P =0.021) , and DA +NE group was 20.0%.28 days mortality rate in DA group was 24.62%, but in NE group, the mortality rate was 21.54%, and DA +NE group was 18.57%.There was no significant difference the three (χ2=0.725;P =0.394) .Conclusion:In the treatment of shock, norepinephrine has more obvious advantages in terms of stabilizing the heart rate and reducing renal damage compared with dopamine, which is the best drug to treat shock.关键词
多巴胺/去甲肾上腺素/休克Key words
Dopamine/Norepinephrine/Shock引用本文复制引用
杨璇,李长江,冯磊,延荣强,李玉..多巴胺与去甲肾上腺素在休克治疗中的应用研究[J].河北医学,2015,(8):1419-1423,5.基金项目
山东省青岛市卫生局课题支持项目， （）
