河北医学Issue(10)：1594-1597,4.DOI:10.3969/j.issn.1006-6233.2015.10.004
两种肝门阻断切除术式对巨大肝癌患者健侧肝组织功能的影响
Two Kinds of Block Resection of Hepatic Portal on Contralateral Non-tumor Liver Function of Patients with Huge Liver Cancer
摘要
Abstract
Objective:To investigate influence differences of two kinds of block resection on contralater-al non-tumor liver function of patients with hepatic portal huge liver cancer .Methods:80 patients with huge liver cancer were chosen in recent years in our hospital and randomly divided into both group including group A ( 40 patients ) with first hepatic portal completely blocking anterograde resection and group B ( 40 pa-tients) with selective blocking retrograde resection; and the levels of apoptosis index ( AI) of contralateral non-tumor liver tissue and intracellular calcium ion concentration , malondialdehyde ( MDA ) , superoxide dismutase ( SOD) and liver function indexes after operation of both groups were compared .Result:The lev-els of AI of contralateral non-tumor liver tissue after operation of group B was significantly lower than group A (P<0.05).The levels of intracellular calcium ion concentration , MDA and SOD of contralateral non-tumor liver tissue after operation of group B was significantly lower than group A ( P<0.05 ) .The levels of ALT, AST and TBil after operation of B group was significantly lower than group A (P<0.05).The level of PA after operation after operation of group B was significantly higher than group A (P<0.05).Conclusion:Compared with first hepatic portal completely blocking anterograde resection , selective blocking retrograde resection in treatment of patients with huge liver cancer can efficiently protect contralateral non -tumor liver function and alleviate the severity of ischemia reperfusion injury .关键词
肝切除/血流阻断/肝/癌/肝功能Key words
Liver resection/Vascular occlusion/Liver cancer/Liver function引用本文复制引用
柯延壮,侯本新,刘松平,冯强..两种肝门阻断切除术式对巨大肝癌患者健侧肝组织功能的影响[J].河北医学,2015,(10):1594-1597,4.基金项目
海南省卫生厅课题， （）
