郑州大学学报（医学版）Issue(1)：107-109,3.DOI:10.13705/j.issn.1671-6825.2015.01.031
右美托咪定对丙泊酚全麻患者恢复期脑电双频指数和血流动力学的影响
Effect of dexmedetomidine on bispectral index and haemodynamics during propofol anesthesia recovery period
摘要
Abstract
Aim:To observe the effect of dexmedetomidine on bispectral index ( BIS) and haemodynamics during the propofol anesthesia recovery period .Methods:Forty patients with general anesthesia at ASAⅠorⅡlevel were selected and randomly allocated into 2 groups:dexmedetomidine group(1 μg/kg) and control group.Corresponding medicines were in-jected through vein before anesthesia induction and the injection was completed within 15 min.The heart rate(fH),mean ar-terial pressure(pMA) and BIS were recorded before anesthesia induction ,when the sputum suction,at the end of tracheal ex-tubation and 1, 5, 10 min after tracheal extubation .Results: There were significant differences in fH ( Fgroup =23.635, Ftime =13.421,P<0.05) and pMA(Fgroup =3.790,Ftime =3.461,P<0.05) between the 2 groups.At the sputum suction, extubation and 1 and 5 min after the extubation,compared with control group,fH and pMA of dexmedetomidine group were higher(P<0.05).There was no statistical difference in BIS between dexmedetomidine group and control group at different time points(P>0.05).Conclusion:The use of 1μg/kg dexmedetomidine before anesthesia induction does not effect BIS during propofol anesthesia recovery period , and brings stable haemodynamics during propofol anesthesia recovery period .关键词
右美托咪定/脑电双频指数/血流动力学Key words
dexmedetomidine/bispectral index/haemodynamics分类
医药卫生引用本文复制引用
李廷坤,汪蕾,孙亚林,吕帅国,王根生,卢锡华..右美托咪定对丙泊酚全麻患者恢复期脑电双频指数和血流动力学的影响[J].郑州大学学报（医学版）,2015,(1):107-109,3.基金项目
河南省医学科技攻关项目200903145 （）
