中医学报Issue(4)：548-550,3.DOI:10.16368/j.issn.1674-8999.2015.04.189
中医药动物实验研究的再思考
The Reconsideration of Animal Experimental Study of Traditional Chinese Medicine
摘要
Abstract
Thinking over the future of animal experiment of traditional Chinese medicine have five points:①the ethical issues of animal experiments of traditional Chinese medicine:improve the living conditions for experimental animals,put an end to cruelty of experimen-tal animals,standard of the technical operation of animal experiments,establish animal ethical committee and the professor group,re-search progress of advancing the "3R"(reduction,majorization,replacement).② Animal experiments of traditional Chinese medicine must be fully embody the basic characteristics of TCM:Based on the theory of TCM syndrome differentiation and treatment,by the etiol-ogy and pathogenesis of TCM,use a variety of methods copy"malady" of animal model,then use drug reduction to absurdity inspection"malady" model.③To strengthen the clinical research of traditional Chinese medicine,pay attention to human body science:establish-ment of the TCM syndrome depends on inspection,auscultation and olfaction,inquiry,and pulse-taking and palpation,evidence of tradi-tional Chinese medicine is difficult to reflect on animals,the nature qualitative difference of human and animals. The clinical patients must be as the carrier,and should be in the human body on the basis of syndrome standardization study the basis of TCM syndrome.④To establish Chinese medicine syndrome animal evaluation standard:Optimization of animal building factors,the establishment of animal model evaluation method,select has the characteristic of evaluation index.⑤Animal experimental study of TCM to return to the tradi-tional Chinese medicine clinical reality:in animal studies,to link up the standardization of experimental and the authenticity of clinical, experimental study is not only for the purpose of the mechanism,in order to paper,for the sake of so-called science,more research re-sults to be practical,can have an effect in the real open environment,make research of traditional Chinese medicine return to nature,re- <br> turn to the real world,let the theory research is consistent with the real world.关键词
中医药/动物实验/证候模型Key words
traditional Chinese medicine/experiments on animals/symptomatic model分类
医药卫生引用本文复制引用
王灿,苗艳艳,苗明三..中医药动物实验研究的再思考[J].中医学报,2015,(4):548-550,3.基金项目
河南省高校科技创新团队项目（2012IRT STHN011）；郑州市科技创新团队项目（131PCXTD612）；河南中医学院中药新药创制与道地药材深加工协同创新中心项目｛〔2012〕188-2｝ （）
