化工进展Issue(6)：1556-1562,7.DOI:10.3969/j.issn.1000-6613.2014.06.033
2,3,5,6-四氨基吡啶及其（2-羟基）对苯二甲酸复合盐的合成
Synthesis of 2,3,5,6-tetraaminopyridine and its 2-hydroxyterephthalic acid composite salt
摘要
Abstract
In order to prepare the composite salt of 2,3,5,6-tetraaminopyridine and 2-hydroxyterephthalic acid (TH salt) with high purity and yield,the 2,3,5,6-tetraaminopyridine hydrochloride(TAPH) was successfully reduced by catalytic hydrogenation from 3,5-dinitropyridine-2,6-diamine(DADNP) as raw material. TAPH was obtained with the purity of 99.4%and the yield of 82.1%in hydrogen and 55~60℃ condition,the solvent is methanol and the catalyst is Pd/C. Under the protection of the nitrogencondition,the TAPH and 2-hydroxyterephthalic acid(HTA) sodiumsalt were taken as raw materials to make the composite salt of 2,3,5,6-tetraaminopyridine with 2-hydroxyterephthalic acid(TH salt). All chemical structures of the products were identified by 13C-NMR,MS and FT-IR,the result showed that the product was the aim product and its purity was up to 98%.关键词
2,3,5,6-四氨基吡啶/2-羟基对苯二甲酸复合盐/2,3,5,6-四氨基吡啶盐酸盐/2-羟基对苯二甲酸/2,6-二氨基-3,5二硝基吡啶Key words
2,3,5,6-tetraaminopyridine/2-hydroxyterephthalic acid composite salt (TH salt)/2,3,5,6-tetraaminopyridine hydrochloride(TAPH)/2-hydroxyterephthalic acid(HTA)/3,5-dinitropyridine-2,6-diamine(DADNP)分类
化学化工引用本文复制引用
杨健,金宁人,张青龙,张清义..2,3,5,6-四氨基吡啶及其（2-羟基）对苯二甲酸复合盐的合成[J].化工进展,2014,(6):1556-1562,7.基金项目
江苏省科技支撑计划项目（BE 2011129）。 （）
