化工学报Issue(12)：4935-4941,7.DOI:10.3969/j.issn.0438-1157.2014.12.039
基于EM算法的青霉素发酵过程多阶段融合建模
Multi-stage fusion modeling for penicillin fermentation process based on EM algorithm
摘要
Abstract
Penicillin fermentation process has the feature of the distinct phases, which can be seen from some key operating variables. In this paper, the key process variable, namely, the cold water flow rate was taken as the scheduling variable, which was then classified by the fuzzy C-means clustering algorithm. The cluster centers were considered as the main operating points of the penicillin fermentation process. Local models were constructed around each operating point based on EM algorithm. Thereafter, sub-models were combined togethter according to the posterior distribution of the scheduling variable. The feasiblity and effectiveness of the proposed method was illustrated through the Pensim simulation platform.关键词
EM算法/模糊C均值聚类算法/青霉素发酵过程/融合建模Key words
EM algorithm/fuzzy C-means clustering algorithm/penicillin fermentation process/fusion modeling分类
信息技术与安全科学引用本文复制引用
熊伟丽,姚乐,徐保国..基于EM算法的青霉素发酵过程多阶段融合建模[J].化工学报,2014,(12):4935-4941,7.基金项目
国家自然科学基金项目(21206053，21276111)；江苏高校优势学科建设工程资助项目(PAPD)。@@@@supported by the National Natural Science Foundation of China (21206053,21276111) and by the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD) （21206053，21276111）
