哈尔滨商业大学学报（自然科学版）Issue(4)：395-397,401,4.
丁香苦苷 PLGA 纳米粒的体外释放研究
Study on release in vitro of Syringopicroside PLGA nanoparticles
摘要
Abstract
In order to study the vitro release profile of Syringopicroside PLGA nanoparticles , the dynamic dialysis technology was employed to study the in vitro release ability of SYR -NP and Syringopicroside solution .The content of Syringopicroside was determined by HPLC , and the fitting of different models were performed based on the accumulative drug release percentages .The release curve of Syringopicroside PLGA nanoparticles was in line with Higuchi equation , Q=0.128 1+0.018 9t1/2 ( r=0.956 8) .Compared with the Syringopi-croside solution , SYR-NP has a satisfactory sustained release effect .关键词
丁香苦苷/PLGA纳米粒/体外释放Key words
Syringopicroside/PLGA nanoparticles:drug release in vitro分类
医药卫生引用本文复制引用
封文静,管庆霞,张亮,李梦雪,李永吉..丁香苦苷 PLGA 纳米粒的体外释放研究[J].哈尔滨商业大学学报（自然科学版）,2014,(4):395-397,401,4.基金项目
国家自然基金面上项目 （）
