华侨大学学报(自然科学版)Issue(1):60-63,4.DOI:10.11830/ISSN.1000-5013.2015.01.0060
抗氧化剂阿魏酸自组装金纳米颗粒的体外抗氧化
In Vitro Antioxidant Activity Study of Ferulic Acid Self-Assembled Gold Nanoparticles
摘要
Abstract
The antioxidant protection effects of ferulic acid nanoantioxidant on macrophage cells were studied and the free radical-inhibiting activities of ferulic acid nanoantioxidant were determined at the cellular level using electron spin reso-nance-spin trapping and UV-spectrum method.The results illustrates that the nanoantioxidant could eliminate the reactive oxygen species stimulated by t-BuOOH in cells more effectively than that of antioxidants monomers.Meanwhile,the lipid peroxide detection of malondialdehyde by spectrum method also proved that the nanoantioxidant have a high antioxidant activity on t-BuOOH stimulated macrophage cells.Therefore,it could be concluded that the self-assembled nanoantioxi-dant have a potential for the enhancement of antioxidant activity.关键词
电子自旋共振/抗氧化剂/自旋捕获/纳米金/脂质过氧化Key words
electron spin resonance/antioxidant/spin trapping/gold nanoparticles/lipid peroxide分类
数理科学引用本文复制引用
张晗,李砚超,姜玉刚,杜立波,施维,刘扬..抗氧化剂阿魏酸自组装金纳米颗粒的体外抗氧化[J].华侨大学学报(自然科学版),2015,(1):60-63,4.基金项目
国家自然科学基金资助项目 ()