华西口腔医学杂志Issue(1)：93-97,5.DOI:10.7518/hxkq.2015.01.021
地图舌危险因素的研究进展
Research progress on the risk factors of geographic tongue
摘要
Abstract
Geographic tongue, also called benign migratory glossitis, is a common and superficial benign inflammatory disorder that affects the tongue epithelium. The majority of geographic tongue lesions typically manifest as irregular central erythematous patches. These lesions, which are caused by the loss of filiform papillae, are defined by an elevated whitish band-like border that can change location, size, and pattern over a period of time. Histological observations of the oral mucosa affected by geographic tongue revealed nonspecific inflammation. Some reports described cases of migratory stomatitis, wherein lesions simultaneously manifested on the extra lingual oral mucosa. This condition is also called ectopic geographic tongue, which is clinically and histologically similar to the type normally confined to the tongue. In most cases, patients are asymptomatic and do not require treatment. The condition may spontaneously exhibit periods of remission and exacerbation with good prognosis. The specific etiology of geographic tongue remains unknown. Geographic tongue is age-related and is prevalent among young individuals. Various etiological factors that have been suggested in literature include immunological factors, genetic factors, atopic or allergic tendency, emotional stress, tobacco consumption, hormonal disturbances, and zinc deficiency. Geographic tongue may coexist with other disorders, such as fissured tongue, psoriasis, diabetes mellitus, gastroin-testinal diseases, burning mouth syndrome, and Down syndrome. Experts currently disagree on whether geographic tongue is an oral manifestation of psoriasis. Moreover, some scholars suggest that geographic tongue is a prestage of fissured tongue. The objective of this review is to summarize current research on risk factors of geographic tongue.关键词
地图舌/游走性舌炎/危险因素Key words
geographic tongue/migratory glossitis/risk factors分类
医药卫生引用本文复制引用
杨华梅,周瑜,曾昕,廖玍,陈谦明..地图舌危险因素的研究进展[J].华西口腔医学杂志,2015,(1):93-97,5.基金项目
国家自然科学基金创新团体资助项目（81321002）；科技部国际合作基金资助项目（2012DFA31370）；国家自然科学基金资助项目（81102060）；高等学校博士学科点专项科研基金资助项目 （）
