杭州师范大学学报（自然科学版）Issue(4)：378-384,7.DOI:10.3969/j.issn.1674-232X.2015.04.008
C2对称手性四氮配体的合成、结构及催化苯乙酮不对称氢转移反应研究
Synthesis and Structures of C2-symmetric Chiral Tetraaza Ligands and Asymmetric Transfer Hydrogenation of Acetophenone
摘要
Abstract
Four C2‐symmetric chiral tetraaza ligands (2a‐d ) are synthesized and used in asymmetric transfer hydrogenation of acetophenone in 2‐propanol/KOH . The catalysis reaction exhibits good conversion (90% ~ 98% ) and moderate enantiometric excess (2% ~60% ) .Ligand 2d{(R ,R ,S ,S ,S ,S)‐1 ,3‐Di[4 ,5‐diphenyl‐1‐(p‐toluenesulfonyl)‐2‐imidazolidine] benzene}is characterized by X‐ray crystallography ,crystallizing in monoclinic P121 1 chiral space group with Z=2 ,a=10 .4814(6) ,b=9 .4332(5) ,c=21 .8758(14)Å ,V =2161 .7(2)Å3 ,Mr=829 .01 ,Dc=1 .274 g/cm3 ,F(000)=872 ,the final GOF=1 .023 ,R=0 .0518 and wR=0 .1096 .关键词
不对称氢转移/TsDPEN/Ru(p-cymene)Cl2 2/手性四氮配体/苯乙酮Key words
asymmetric transfer hydrogenation/TsDPEN/[Ru(p-cymene)Cl2 ]2/chiral tetraaza ligand/acetophenone分类
化学化工引用本文复制引用
俞黄琴,刘训高,沈良..C2对称手性四氮配体的合成、结构及催化苯乙酮不对称氢转移反应研究[J].杭州师范大学学报（自然科学版）,2015,(4):378-384,7.基金项目
浙江省公益基金项目（2012C21098）． （）
