激光生物学报Issue(2)：158-164,7.DOI:10.3969/j.issn.1007-7146.2015.02.008
3 D-PDU S对成人常染色体显性遗传多囊肾病肾脏血流动力学变化的研究
Assessment of the Renal Vascular Changes of Hemodynamies in Patients with Autosomal Dominant Polycystie Kidney Disease by 3 D-PDUS
摘要
Abstract
Objective:To assess the relationship between renal vascular changes of hemodynamics and blood pressure in patients with autosomal dominant polycystic kidney disease(ADPKD)by 3D-PDUS.Methods:The hemodynamic pa-rameters of Vascularization index (VI),Flow index (FI),total kidney volume (TKV)of renal segmental arteries and in-terlobar arteries were measured separately by 3D-PDUS imaging in 79 patients with ADPKD.62 patients with essential hypertension(EH)and 24 healthy people.Results:(1 )When the blood pressure was normal,the volume of the kidney became bigger and VI declined(P<0.05)in ADPKD patients;VI dramatic declined and the volume of the kidney markedly augmented(P<0.01)in renal aorta and inter lobar arterial.(2)VI and BP grade are negative correlated,but TKV and BP grade are positive correlated instead in ADPKD group.(3 )Doppler indices of hemodynamic in ADPKD correlated significantly with blood pressure changes.Conclusions:Doppler indices do reflect the changes of hemodynam-ics in patients with ADPKD,and are closely related with the development of systemic arterial hypertension and the ultra-sonographic abnormality of kidney.关键词
常染色体显性多囊肾/三维能量多普勒/血压/肾动脉/血流灌注Key words
autosomal dominant polycystic kidney disease/3 D-PDUS/blood pressure/renal artery/hemodynamics分类
医药卫生引用本文复制引用
陈妮妮,陈志恒..3 D-PDU S对成人常染色体显性遗传多囊肾病肾脏血流动力学变化的研究[J].激光生物学报,2015,(2):158-164,7.基金项目
湖南省科技厅科技计划一般项目体检人群血管健康规范化管理研究（2014SK3062）；湖南省工程技术研究中心建设项目湖南省亚健康诊断与干预工程技术研究中心 （）
