江汉大学学报（自然科学版）Issue(6)：78-81,4.
菜豆植物凝集素对小鼠骨髓细胞微核发生率的影响
Analysis on Micronucleus Formation Induced by Kidney Bean Lectin
牟龙妹 1刘宜子 1李佳楠1
作者信息
- 1. 江汉大学 生命科学学院生物技术系，湖北 武汉 430056
- 折叠
摘要
Abstract
Objective To research the effect on micronucleus formation induced by lectin from vari⁃eties of kidney beans. Methods Giving the mice lectin of three kind of kidney beans by intraperito⁃neal injection for 6 days. Bone marrow cells were collected and microscope slides were prepared by Giemsa staining. Micronucleus ratio was analysed under a light microscope, then judged the mutagenic effect of different kidney bean lection. Results There was no significant difference between experi⁃ment group and negative control group, but positive group was obviously higher than experiment group and negative control group(P<0. 05). Micronucleus ratio had a dose-effect relationship, but it was independent with gender. Conclusion The three levels of lectin of three kind of kidney beans have no effect on micronucleus formation of bone marrow cells in mice, they can be used for development of biological preparations.关键词
菜豆/植物凝集素/微核试验/致突变作用Key words
kidney bean/lectin/micronucleus test/mutagenic effect分类
医药卫生引用本文复制引用
牟龙妹,刘宜子,李佳楠..菜豆植物凝集素对小鼠骨髓细胞微核发生率的影响[J].江汉大学学报（自然科学版）,2014,(6):78-81,4.
