江汉大学学报（自然科学版）Issue(1)：84-87,4.DOI:10.16389/j.cnki.cn42-1737/n.2015.01.014
腹外侧视前区微量注射组胺对大鼠睡眠-觉醒周期的影响
Effects of Microinjection of Histamine in Ventrolateral Preoptic Area on Rat Sleep-Wakefulness Cycle
摘要
Abstract
Objective To study the effect of histamine in rat ventrolateral preoptic area on sleep-wakeful⁃ness cycle. Methods Histamine was microinjected into ventrolateral preoptic area through stereotaxic technique,sleeping and waking time phases were recorded and analyzed by electroencephalograph. Results Microinjection of 50 μmol/L histamine had no significant effect ,but 100 μmol/L histamine de⁃creased sleeping time and increased waking time significantly. Conclusion Histamine is involved in reg⁃ulation of sleep-waking cycle and promotes wakefulness significantly in the ventrolateral preoptic area.关键词
组胺/腹外侧视前区/睡眠-觉醒周期Key words
histamine/ventrolateral preoptic area/sleep-wakefulness cycle分类
医药卫生引用本文复制引用
刘宇炜,若剑,陈晓青,易卉玲,黄丹..腹外侧视前区微量注射组胺对大鼠睡眠-觉醒周期的影响[J].江汉大学学报（自然科学版）,2015,(1):84-87,4.基金项目
国家自然科学基金面上项目（31371090）；武汉市科技计划项目 （）
