江汉大学学报（自然科学版）Issue(2)：111-115,5.DOI:10.16389/j.cnki.cn42-1737/n.2015.02.003
ClC-0氯离子通道蛋白质空间结构的同源建模
Homology Modeling of Spatial Structure of CIC-0 Chloride Channel Proteins
摘要
Abstract
CIC-type chloride ion channel proteins play important role in regulating the metabolism process of biological system. On the base of CIC-ec1 crystal structure,in accordance with the principle of homology modeling,using SWISS-MODEL net server,constructed the spatial structure of a kind of CIC-0 chloride ion channel protein , and analyzed the reasonableness of the obtained structure. Through measuring the Z-score of the structure ,analyzing the fluctuation of space coordinates of the structure , and comparing the modeling CIC-0 structure with template structure,discovered that the spatial structure of CIC-0 protein by homology modeling complied with the requirement of further study ,which makes the further simulation and computation be easy.关键词
同源建模/氯离子通道蛋白质/SWISS-MODELKey words
homology modeling/chloride channel protein/SWISS-MODEL分类
生物科学引用本文复制引用
于涛,朱紫洪,郝栋梁,彭黎,张攀,徐号,郭旭..ClC-0氯离子通道蛋白质空间结构的同源建模[J].江汉大学学报（自然科学版）,2015,(2):111-115,5.基金项目
国家自然科学基金项目（11304123）；国家留学基金项目（201408420100）；江汉大学高层次人才科研启动经费项目（2013016）；江汉大学学生科研项目 （）
