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纳洛酮对急性酒精中毒患者抗氧化能力状态影响的研究

袁锋 李长罗

中国当代医药Issue(16):85-86,2.
中国当代医药Issue(16):85-86,2.

纳洛酮对急性酒精中毒患者抗氧化能力状态影响的研究

Study of influence of naloxone on the antioxidant capacity of patients with acute alcoholism

袁锋 1李长罗1

作者信息

  • 1. 长沙市中心医院急诊科,长沙 410000
  • 折叠

摘要

Abstract

Objective To explore the influence of naloxone on the antioxidant capacity of patients with acute alco-holism. Methods 60 patients with acute alcoholism were treated in our hospital from February 2012 to January 2014, and they were randomly divided into treatment group and the control group,there were 30 cases in each group,the con-trol group was given conventional treatment,the treatment group was given naloxone on the basis of the control group, the antioxidant capacity of the two groups before and after treatment were compared. Results After 24 hours treatment, the TAC,CAT increased,but the rise in treatment group was obviously higher than that of the control group;MDA and LPO decreased,but the reduction in the treatment group was obviously greater than the control group (P<0.05). There was no statistical difference of the incidence rate of adverse reactions in the two groups (P>0.05). Conclusion The influence of naloxone on the antioxidant capacity of patients with acute alcoholism bigger,it can improve the prognosis of patients.

关键词

纳洛酮/急性酒精中毒/抗氧化能力

Key words

Naloxone/Acute alcohol poisoning/Antioxidant capacity

分类

医药卫生

引用本文复制引用

袁锋,李长罗..纳洛酮对急性酒精中毒患者抗氧化能力状态影响的研究[J].中国当代医药,2014,(16):85-86,2.

中国当代医药

1674-4721

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