中国当代医药Issue(23)：76-77,80,3.
厄贝沙坦联合硝苯地平控释片治疗高血压的效果
Effect of irbesartan combined with nifedipine controlled release tablet in the treatment of hypertension
龙文1
作者信息
- 1. 江西省吉安县人民医院心内科，江西吉安 343100
- 折叠
摘要
Abstract
Objective To explore the effect of irbesartan combined with nifedipine controlled release tablet in the treat-ment of hypertension. Methods 80 cases of patients with hypertension were selected and randomly divided into two groups.In observation group,patients were treated by irbesartan combined with nifedipine controlled release tablet,while in control group,metoprolol combined with nifedipine controlled release tablet were provided.The renal function,mean arterial pressure and change of ultrasonic cardiogram after treatment in two groups was compared respectively. Results After therapy,the levels of urea nitrogen and creatinine,mean arterial pressure in the observation group was greatly low-er than that in the control group respectively,with statistical difference(P<0.05).The interventricular septal thickness and left ventricular end diastolic diameter in the observation group after treatment was remarkably less than that in the con-trol group respectively,with statistical difference (P<0.05).The left ventricular ejection fraction in the observation group was higher than that in the control group,with statistical difference (P<0.05). Conclusion Irbesartan combined with nifedipine controlled release tablet play a more obvious reverse effect on left ventricle hypertrophy in hypertension pa-tient,better control patient’s blood pressure and protect renal function simultaneously.关键词
厄贝沙坦/美托洛尔/硝苯地平/高血压/左室肥厚Key words
Irbesartan/Metoprolol/Nifedipine/Hypertension/Left ventricle hypertrophy分类
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龙文..厄贝沙坦联合硝苯地平控释片治疗高血压的效果[J].中国当代医药,2014,(23):76-77,80,3.
