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胸腺肽α1治疗老年晚期恶性肿瘤的效果分析

王纯 米利群 费晓东 潘琴 杨燕峰

中国当代医药Issue(23):101-102,105,3.
中国当代医药Issue(23):101-102,105,3.

胸腺肽α1治疗老年晚期恶性肿瘤的效果分析

Effect analysis of thymosin α1 in the treatment of elderly patients with advanced malignant tumor

王纯 1米利群 1费晓东 1潘琴 1杨燕峰1

作者信息

  • 1. 江苏省溧阳市人民医院肿瘤内科,江苏溧阳 213300
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摘要

Abstract

Objective To study and analyze the clinical effect of thymosin α1 in the treatment of elderly patients with advanced malignant tumor. Methods Sixty cases of elderly patients with advanced malignant tumor accepted treatment in our hospital from January 2012 to September 2013 were selected and evenly divided into observation group and control group in random.In the control group,patients were provided with regular treatment,while in the observation group,on the basis of the control group,thymosin α1 was added.The therapeutic effect and adverse reaction in the both groups was compared respectively. Results The total effective rate in the observation group was 60.0%,higher than that in the control group(30.0%),with a statistical difference(P<0.05).There was no statistical difference in incidence rate of adverse reaction between two groups (P>0.05).Before treatment,cellular immune function in both groups was compared, with no statistical difference (P>0.05).After therapy,CD4/CD8 and the percentage of natural killer positive cell in the observation group was higher than that in the control group respectively (P<0.05). Conclusion Application of thymosinα1 in the treatment of advanced malignant tumors in the old can obtain a definite effect with few adverse reaction,which is worthy of expansion and application in clinic.

关键词

胸腺肽α1/老年患者/晚期恶性肿瘤

Key words

Thymosinα1/Elderly patient/Advanced malignant tumor

分类

医药卫生

引用本文复制引用

王纯,米利群,费晓东,潘琴,杨燕峰..胸腺肽α1治疗老年晚期恶性肿瘤的效果分析[J].中国当代医药,2014,(23):101-102,105,3.

中国当代医药

1674-4721

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