摘要
Abstract
Objective To investigate the prediction vaule of pepsinogenⅠ combined with gastrin-17 in lesion location of chronic atrophic gastritis and the period of gastric cancer progression. Methods 33 cases with chronic atrophic gas-tritis and 35 cases in the different period of gastric cancer in our hospital were selected as research objects.All these participants were detected by pegsinogenⅠ,pegsinogenII and gastrin-17.The level of pegsinogenⅠ,pegsinogenII and gastrin-17 were compared and analyzed. Results The level of pepsinogens I and gastrin-17 in chronic atrophic gastri-tis group were higher than that in gastric cancer group,with statistical difference(P<0.05).Pepsinogen I level in the gas-tric antrum of chronic atrophic gastritis was higher than that in the gastric body and the total diffuse,with statistical dif-ference (P<0.05),the gastrin-17 level in the gastric body was higher than that in the total diffuse and in the gastric antrum,with statistical difference (P<0.05).Pepsinogen I and gastrin-17 lever of early gastric cancer and carcinoma in situ were higher than advanced gastric carcinoma,with statistical difference (P<0.05). Conclusion The gastrin-17 in gastric antrum of chronic atrophic gastritis decreases significantly,pepsinogen I fell more sharply in the gastric body and the total diffuse,pepsinogen I level decreases significantly and the gastrin-17 level increases significantly with progres-sion of gastric cancer.关键词
胃蛋白酶原Ⅰ/胃泌素-17/预测/慢性萎缩性胃炎部位/胃癌进展Key words
PepsinogenⅠ/Gastrin-17/Prediction/Lesion location of chronic atrophic gastritis/Progression of gastric carcinoma分类
医药卫生
