中国当代医药Issue(28)：22-23,26,3.
左炔诺孕酮宫内缓释系统联合促性腺激素释放激动剂治疗子宫内膜异位症的临床效果
Clinical effect of LNG-IUS combined with GnRH-a in the treatment of endometriosis
吉敏1
作者信息
- 1. 江西铜业集团(德兴)医院妇产科，江西德兴 334224
- 折叠
摘要
Abstract
Objective To investigate clinical effect of levonorgestrel-releasing intrauterine system (LNG-IUS)combined with gonadotropin releasing agonist(GnRH-a)in the treatment of endometriosis. Methods 96 patients with endometriosis were divided into LNG-IUS group,GnRH-a group and combined group,each group of 32 cases.LNG-IUS and GnRH-a was used in LNG-IUS group and GnRH-a group respectively,and combined with two treatment methods were applied in combined group. Results 1 year clinical total effective rate of GnRH-a group and combined group was 100.0% re-spectively,significantly higher than that of LNG-IUS group respectively (87.5%) (P<0.05).2 years recurrence rate of GnRH-a group was 35.3%,significantly higher than that of LNG-IUS group(8.3%)and combined group(13.3%) respec-tively (P<0.05),while 2 years recurrence rate of GnRH-a group compared with combined group had no statistical differ-ence(P>0.05).Follow-up of 1 year,bone mineral density of GnRH-a group and combined group compared with before treatment respectively,with statistical difference(P<0.05).Follow-up of 2 year,bone mineral density of three groups com-pared with before treatment respectively,with no statistical difference (P>0.05). Conclusion The integral effect of LNG-IUS combined with GnRH-a in the treatment of endometriosis is more significant than when they are used alone,combi-nation scheme can be used as a clinical choice in the treatment of endometriosis.关键词
子宫内膜异位症/左炔诺孕酮宫内缓释系统/促性腺激素释放激动剂Key words
Endometriosis/Levonorgestrel-releasing intrauterine system/Gonadotropin releasing agonist分类
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吉敏..左炔诺孕酮宫内缓释系统联合促性腺激素释放激动剂治疗子宫内膜异位症的临床效果[J].中国当代医药,2014,(28):22-23,26,3.
