摘要
Abstract
Objective To analyze the clinical effect of different dosage regimen amoxicillin and clavulanate potassium in the treatment of bacterial respiratory tract infections. Methods 936 patients with bacterial respiratory tract infection treated in our hospital from June 2011 to June 2013 were randomly divided into group A and group B,group A were given with injections of amoxicillin and clavulanate potassium 100 mg/kg,dissolved in 100 ml of sodium chloride injec-tion,intravenous injection,1 time/d.Group B were taken with the same batch of injectable amoxicillin and clavulanate potassium,50 mg/kg,dissolved in 50 ml of sodium chloride injection,intravenous injection,2 times/d.According to the disease,administration time were 1 to 2 weeks.The clinical efficacy of the two groups and the administration time were compared. Results In patients with mild and moderate infection,the administration time of group A and group B had no significant difference (P>0.05);in patients with severe infection,the administration time of group A was longer than that of group B,the difference was significant (P<0.05).In patients with mild and moderate infection,the effective rate of group B was higher than that of group A,but the difference was not significant (P>0.05);in patients with severe infection, the effective rate of group B was higher than that of group A,the difference was significant (P<0.05). Conclusion The dosage regimen of group A has better effect in patients with mild and moderate infection,can decrease the administra-tion time,the dosage regimen of group B has better effect in patients with severe infection.关键词
阿莫西林克拉维酸钾/不同给药方案/细菌性呼吸道感染Key words
Amoxicillin and clavulanate potassium/Different dosage regimen/Bacterial respiratory infections分类
医药卫生
