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二甲双胍在多囊卵巢综合征促排卵治疗中的应用效果

苏静芳

中国当代医药Issue(32):104-105,108,3.
中国当代医药Issue(32):104-105,108,3.

二甲双胍在多囊卵巢综合征促排卵治疗中的应用效果

Application effect of metformin in stimulating ovulation treatment of polycystic ovary syndrome

苏静芳1

作者信息

  • 1. 江苏省常熟市第一人民医院妇科,江苏常熟 215500
  • 折叠

摘要

Abstract

Objective To explore the application effect of metformin in stimulating ovulation treatment of polycystic o-vary syndrome. Methods 56 cases with polycystic ovary syndrome from January 2012 to January 2014 in our hospital were selected and randomly divided into control group and observation group,28 cases in each group.The control group were treated with intramuscular injection of gonadotropin,the observation group were treated with metformin.The level of LH,INS,FSH,T,LH/FSH and ovulation of two groups before and after treatment was compared respectively. Results The ovulation rate of observation group was 92.86% and the pregnancy rate of observation group was 75.00%,the ovulation rate of the control group was 67.86%and the pregnancy rate of observation group was 32.14%,there was significant dif-ference(P<0.05).In addition,the level of LH,INS,FSH,T,LH/FSH of the observation group after treatment was significant-ly better than that before treatment and control group respectively,with statistical difference (P<0.05). Conclusion Met-formin can significantly reduce the fasting insulin level,improve the abnormal symptoms of sex hormone,promote ovula-tion and pregnancy recovery,the rate of adverse reaction is low,and safety is high,which is worthy of further application in the treatment of polycystic ovary syndrome.

关键词

多囊卵巢综合征/二甲双胍/促排卵/作用

Key words

Polycystic ovary syndrome/Metformin/Stimulating ovulation/Role

分类

医药卫生

引用本文复制引用

苏静芳..二甲双胍在多囊卵巢综合征促排卵治疗中的应用效果[J].中国当代医药,2014,(32):104-105,108,3.

中国当代医药

1674-4721

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