摘要
Abstract
Objective To investigate the effect and safety of etomidate combined with sufentanyl in elderly patients un-dergoing palnless colonoscopic examination. Methods 60 elderly patients undergoing palnless colonoscopic examination in our hospital from August 2013 to October 2014 were selected,with ASalI-Ⅲ,were randomly divided into group P (propofol group),group E1 (etomidate group) and group E2 (etomidate combined with small doses sufentanyl group),20 cases in each group.Intravenous injection of propofol (1.5-2.5 mg/kg) was taken to group P,intravenous injection of eto-midate (0.2-0.35 mg/kg) was taken to group E1,group E2 were received intravenous injection of etomidate (0.1-0.3 mg/kg) af-ter who were given with sufentanyl (0.1μg/kg) for a minute.Before anesthesia (T0),after administration into the mirror before (T1),after the mirror 2 minites (T2),after the mirror 5 minites (T3),checking end (T4),wake up (T5),HR,MAP,SpO2 and the recovery time,adverse reactions,satisfaction among the three groups was observed. Results HR,MAP of group P at T1,T2,T3,T4 point dereased compared with that at T0,T5 point,the difference was significant (P<0.05),and HR,MAP of group P at T1,T2,T3,T4 point dereased compared with that of group E1 and group E2,the difference was significant (P<0.05).The incidence of injection paln in group E1,E2 was lower than that in group P (P<0.05).The incidence of nausea and vomiting,body movement,muscle trembling in group P and group E2 was lower than that in group E1 (P<0.05). Conclusion Etomidate combined with small doses sufentanyl can provide effective paln relief with fewer stimulation of the cardiovascular and respiratory system in the elderly patients with palnless colonoscopic examination.关键词
舒芬太尼/依托咪酯/老年患者/肠镜检查Key words
Sufentanyl/Etomidate/Elderly patients/Colonoscopic examination分类
医药卫生
