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抗肝纤方对早期肝硬化门脉高压症患者血流动力学的影响

李龙华 江一平

中国当代医药Issue(12):118-120,123,4.
中国当代医药Issue(12):118-120,123,4.

抗肝纤方对早期肝硬化门脉高压症患者血流动力学的影响

Influence of anti-hepato-fibrosis prescription on hemodynamics in pa-tients with early-stage liver cirrhosis complicated with portal hyperten-sion

李龙华 1江一平1

作者信息

  • 1. 江西中医药大学附属医院脾胃肝胆科,南昌 330006
  • 折叠

摘要

Abstract

Objective To explore the influence of anti-hepato-fibrosis prescription on hemodynamics in patients with early-stage liver cirrhosis and portal hypertension. Methods From January 2013 to May 2014,sixty patients meeting the diagnostic criteria were evenly divided into treatment group and control group by random number table.In the treatment group,anti-hepato-fibrosis prescription was used,while in the control group,propranolole hydrochloride combining with Dahuang Zhechong Capsule was adopted.Change of indexes including diameter of portal vein (DPV),diameter of splenic vein (DSV),spleen venous flow (SVF),portal venous flow (PVF),and hepatic fibrosis before and after treatment were ob-served. Results After treatment,value of HA,PCⅢ,LN,and CⅣ in serum were decreased in both groups,but didn’t dis-play significant difference between two groups.Value of DPV,DSV,and PVF in the two groups were decreased,and value of SVF in the treatment group was significantly decreased (P<0.01).There were statistical differences in values of DSV, PVF,and SVF between two groups after therapy (P<0.05). Conclusion Anti-hepato-fibrosis prescription can effectively alleviate hepatic fibrosis,and also improve hemodynamics in patients with early-stage liver cirrhosis and portal hyper-tension,which is worthy of clinical promotion.

关键词

早期肝硬化/门脉高压症/血流动力学/抗肝纤方

Key words

Early-stage liver cirrhosis/Portal hypertension/Hemodynamics/Anti-hepato-fibrosis prescription

分类

医药卫生

引用本文复制引用

李龙华,江一平..抗肝纤方对早期肝硬化门脉高压症患者血流动力学的影响[J].中国当代医药,2015,(12):118-120,123,4.

基金项目

江西省卫生厅中医药科研基金课题 ()

中国当代医药

1674-4721

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