中国当代医药Issue(13)：141-143,3.
布地奈德联合孟鲁司特钠治疗儿童哮喘的临床研究
Clinical study of budesonide combined with montelukast sodium in the treatment of children with asthma
摘要
Abstract
Objective To evaluate the application effect of inhaled budesonide combined with montelukast sodium chewable tablets in the treatment of children with bronchial asthma. Methods 70 children with mild to moderate chronic persistent bronchial asthma treated in our hospital from May 2013 to May 2014 were selected and randomly di-vided into two groups.35 cases of patients in study group were treated with inhaled budesonide combined with oral montelukast sodium chewable tablets on the bases of the same routine treatment and nursing care while 35 cases of the patients in control group were treated with inhaled budesonide.The asthma symptoms score and the asthma control of the patients between two groups during the follow-up period were compared after one course of drug treatment. Results After one course of treatment,asthma symptom scores in the children between two groups during daytime and night were significantly decreased (P<0.05).Decline in study group was more significant than that in control group (P<0.05).During the follow-up period,the times of acute onset of asthma in study group were significantly less than that in control group (P<0.05).At the same time the rate of symptom free days in study group (87.50%) was significantly higher than 71.43%in control group (P<0.05);There was no serious adverse drug reaction between two groups. Conclusion On the bases of routine treatment,method of inhaled budesonide combined with oral montelukast sodium chewable tablets in the treat-ment of children with chronic persistent bronchial asthma can significantly reduce asthma symptoms and give the long-term control asthma symptoms,which is worthy of clinical application.关键词
布地奈德/孟鲁司特钠/支气管哮喘Key words
Budesonide/Montelukast sodium/Asthma分类
医药卫生引用本文复制引用
李麒,邓成华,袁伟芳,薛萍芳,张涛..布地奈德联合孟鲁司特钠治疗儿童哮喘的临床研究[J].中国当代医药,2015,(13):141-143,3.基金项目
广东省深圳市龙岗区科技计划医疗卫生（非扶持类）项目 （）
