中国当代医药Issue(14)：63-64,67,3.
Ki67表达与乳腺癌新辅助化疗疗效的关系
Relationship between Ki67 expression and curative effect of neoadjuvant chemotherapy for breast cancer
吴昱冶 1黄美玲 1潘妙君1
作者信息
- 1. 广东省农垦中心医院肿瘤内科，广东湛江 524000
- 折叠
摘要
Abstract
Objective To explore the relationship between Ki67 expression and curative effect of neoadjuvant chemotherapy for breast cancer. Methods From January 2010 to January 2014,80 patients with breast cancer accepted neoadjuvant chemotherapy and treated in our hospital were selected.Patients were divided into high expression group (n=57) and low expression group (n=23) according to positive cell proportion of Ki67;patients were divided into de-creased obviously group (n=64) and decreased slightly group (n=16) according to decreased level of Ki67 expression. Miler and Payne (MP)treatment reaction system was used to evaluate the curative effect of pathology. Results Evalua-tion result of MP treatment reaction:the number of cases in grade 1,2,3,4,and 5 was 8,16,49,4,and 3 respectively.The ef-fective rate of pathology in high expression group was obviously higher than that of low expression group (χ²=6.218,P<0.05) and the effective rate of pathology in decreased obviously group was obviously higher than that of decreased slightly group (χ²=10.083,P<0.05). Conclusion Ki67 can be considered as a biological indicator in predicting and eval-uating the curative effect of neoadjuvant chemotherapy on breast cancer.关键词
Ki67/表达/乳腺癌/新辅助化疗/关系Key words
Ki67/Expression/Breast cancer/Neoadjuvant chemotherapy/Relationship分类
医药卫生引用本文复制引用
吴昱冶,黄美玲,潘妙君..Ki67表达与乳腺癌新辅助化疗疗效的关系[J].中国当代医药,2015,(14):63-64,67,3.
