摘要
Abstract
The World Health Organization’s survey shows that diabetes is one of the three major causes of human deaths.Because of the large number of patients with diabetes,the traditional medicine treatment is less specific,the dia-betes drugs with high efficiency,specificity and side effects is the hot issues of drug research.Fibroblast growth factor-21(FGF-21) is a cell growth factor encoded by the members of the FGF gene family, and has a wide range of biological activity.The study shows that it can be independent of the insulin,and have a synergistic effect with insulin.It can sig-nificantly reduce blood glucose and blood lipid levels,improve insulin resistance and islet β-cell function.With the in-depth study,FGF-21 is expected to become a first-line drug with insulin replacement,competition or combination of type 2 diabetes treatment.This paper describes the structure,function and current research progress of FGF-21.关键词
人成纤维细胞生长因子-21/糖尿病/研究进展Key words
Fibroblast growth factor-21(FGF-21)/Diabetes/Research progress分类
医药卫生
