中国当代医药Issue(15)：68-70,3.
低分子肝素联合硫酸镁治疗早发型子痫前期的效果分析
Effect analysis of low molecular weight heparin combined with magne-sium in treatment of early-onset preeclampsia
摘要
Abstract
Objective To investigate the effect of low molecular weight heparin combined with magnesium in treatment of early-onset preeclampsia. Methods 56 patients with early-onset preeclampsia treated in our hospital from January 2012 to January 2014 were selected,and they were randomly divided into observation group and control group,there were 28 cases in each group.Control group was treated with magnesium,while observation group was treated with low molecular weight heparin on the basis of control group.Platelet (PLT) count,prothrombin time (PT),thrombin time (TT), activated partial thromboplastin time (APTT),fibrinogen (FIB) and D-dimer of two groups before and after treatment was compared,postpartum hemorrhage was recorded. Results Before treatment,PLT count,PT,TT,APTT,FIB and D-dimer of two groups had no significant difference (P>0.05);after treatment,PLT count between two groups had no significant dif-ference (P>0.05),PT,TT,APTT of observation group was longer than that of control group respectively,FIB and D-dimer was decreased compared with that of control group,the difference was significant (P<0.05). Postpartum hemorrhage of the observation group was (327.4±78.2) ml,the postpartum hemorrhage of the control group was (274.6±86.7) ml,two groups had no significant difference (P>0.05). Conclusion Low molecular weight heparin and magnesium in treatment of patients with early-onset preeclampsia can significantly improve the hypercoagulable state in patients,and does not increase the risk of bleeding.关键词
早发型子痫前期/硫酸镁/低分子肝素Key words
Early-onset preeclampsia/Magnesium/Low molecular weight heparin分类
医药卫生引用本文复制引用
李战玲,龙海琳,李文娟..低分子肝素联合硫酸镁治疗早发型子痫前期的效果分析[J].中国当代医药,2015,(15):68-70,3.基金项目
广东省茂名市科技计划项目 （）
