中国当代医药Issue(18)：41-43,47,4.
右美托咪定辅助硝酸甘油控制性降压在鼻内镜手术中的应用效果
Application effect of controlled hypotension with dexmedetomidine assist-ing nitroglycerin in endoscopic sinus surgery
王美容 1龚文魁 1陈碧艳 2何妹仪 1李志鹏 1柳垂亮1
作者信息
- 1. 广东省佛山市禅城区中心医院麻醉科，广东佛山 528031
- 2. 广东省佛山市禅城区中心医院护理部，广东佛山 528031
- 折叠
摘要
Abstract
Objective To observe the application effect of controlled hypotension with dexmedetomidine assisting nitro-glycerin in endoscopic sinus surgery. Methods From April 2012 to February 2013,60 patients with ASA Ⅰ-II grade who underwent endoscopic sinus surgery were selected and randomly divided into nitroglycerin group (group N) and Dex combined assist nitroglycerin group (group DN),and there were 30 cases in each group.Mean arterial pressure (MAP),heart rate (HR),blood lactate (Lac) concentration and the numerical of Narcotrend (NT) value before anesthesia (T0),before operation (T1),15min (T2) and 30 min (T3) after reducing the pressure,20 min after stoping reducing the pres-sure (T4) were recorded,and surgical field quality was evaluated,and the incidence rate of agitation during awakening period was recorded respectively. Results Compared with T0,MAP was decreased at T2,T3 (P<0.05) and HR was speeded up at T2-T4 (P<0.05) in group N respectively;MAP at T1-T3, and HR at T1 in group DN was significantly decreased (P<0.05).Compared with group N,MAP and HR was decreased respectively at T1-T4 in group DN (P<0.05).Compared with T0,Lac was increased at T2,T3 in group N and group DN (P<0.05);Surgical field quality score and the incidence rate of agitation during awakening period was lower than that of group N respectively (P<0.05). Conclusion Controlled hy-potension of Dex assisting nitroglycerin with ideal surgical field is more appropriate controlled hypotension method for endoscopic sinus surgery.关键词
右美托咪定/硝酸甘油/控制性降压/鼻内镜手术Key words
Dexmedetomidine/Nitroglycerin/Controlled hypotension/Endoscopic sinus surgery分类
医药卫生引用本文复制引用
王美容,龚文魁,陈碧艳,何妹仪,李志鹏,柳垂亮..右美托咪定辅助硝酸甘油控制性降压在鼻内镜手术中的应用效果[J].中国当代医药,2015,(18):41-43,47,4.
