摘要
Abstract
Objective To analyze the clinical effect of chronic urticaria treated by cetirizine combined with BCG-polysaccharide nucleic acid. Methods 82 patients with chronic urticaria treated in our hospital from January 2013 to December 2014 were selected as research objects and randomly divided into two groups.41 cases in control group,ceti-rizine was provided,while 41 cases in experimental group,cetirizine combined with BCG-polysaccharide nucleic acid was applied.The clinical effect,adverse reaction,and levels of tumor necrosis factor-α(TNF-α) and interferon-γ(INF-γ) before and after treatment was compared respectively. Results The total clinical effective rate in experimental group was 97.6%,while in control group,the rate was 75.6%,with statistical difference(P<0.05).After therapy,there were statis-tical differences in TNF-α [(24.3±5.5) V S (27.0±5.2)] ng/L and IFN-γ [(47.7±11.2) V S (42.6±10.8)] μg/L in experi-mental and control groups(P<0.05).The incidence of adverse reactions between two groups didn't display statistical sig-nificance (P>0.05). Conclusion Cetirizine combined with BCG-polysaccharide nucleic acid can obtain a definite on treating chronic urticaria with few adverse reactions,which is worthy of clinical promotion.关键词
慢性荨麻疹/西替利嗪/卡介菌多糖核酸Key words
Chronic urticaria/Cetirizine/BCG-polysaccharide nucleic acid分类
医药卫生
