摘要
Abstract
Objective:To explore the clinical effect of modified electric convulsive therapy( MECT) on acute psychosis.Methods:60 patients with acute psychosis, who were in our hospital from December, 2013 to January,2014,were divided into drug treatment group( n=30) and MECT treatment group( n=30) in accordance with the admission time.brief psychiatric rating scale( BPRS) ,the Clinical Global Im-pression-Severty of Illness( CGI-SI) and Treatment Emergent Symptom Scale( TESS) were used to eval-uate the curative effect and side effects before the treatment and 1st,2nd,3rd and 4th week after the treat-ment.Results:The total efficiency of the MECT treatment group was 96.67% ,which was significantly higher than that of drug treatment group(46.67%) (P <0.01).There was no significant change in BPRS between two groups before the treatment.BPRS in MECT treatment group was significantly lower than that in the drug treatment group after 1 week (t=3.04,P<0.05),2 week(t=2.75,P<0.05),3 week (t=4.24,P<0.01)and 4 week treatment(t=3.89,P<0.01).The difference in CGI-SI score was no statistical significant between the two groups before and 1 week after the treatment.CGI-SI in MECT treatment group were significantly lower than those in the drug treatment group after 2 week ( t=9.91,P<0.01),3 week (t=6.79,P<0.01)and 4 week treatment(t=6.40,P<0.01).Significant lower incidences of adverse reactions to the drug were observed in the patients in MECT treatment group compared with drug treatment group at 1 week(t=2.40,P<0.05),2week(t=3.35,P<0.05),3week (t=4.15,P<0.01) and 4 week (t=5.53,P <0.01) after the treatment.Conclusion:The effect of MECT is superior to the conventional drug treatment and the side effect of MECT is lower than that of conventional drug treatment,MECT is a safe and effective treatment method for acute psychosis.关键词
重性精神病/急性期/无抽搐电休克治疗/疗效Key words
Acute psychosis/The acute phase/Modified electric convulsive therapy/Treatment effect分类
医药卫生
