健康研究Issue(1)：28-29,32,3.DOI:10.3969/j.issn.1674-6449.2015.01.011
不同剂量缬沙坦治疗慢性心力衰竭的疗效观察
The effect of Valsartan prepared in different doses as used in treating chronic heart failure
陈国英 1徐巧玲 1余丹1
作者信息
- 1. 宁波市镇海龙赛医院 心内科，浙江 宁波315200
- 折叠
摘要
Abstract
Objective To understand the effect of valsartan when prepared in different doses for the treatment of chronic heart failure (CHF).Method 94 subjects were randomly divided into three groups , group A, group B and group C.All groups were firstly treated with conventional treatment and then were given valsartan of 80mg/d once, 160mg/d 2 times, 360mg/d 2 times respectively.The effects of the different doses were examined 4 weeks after and 12 weeks after treatment. Findings The BNP, LVEF, LVEDVI and the total efficiency of group B and group C as observed 4 weeks after and 12 weeks after treatment as compared to those of group were statistically significant (P<0.05).The BNP, LVEF, LVEDV between group B and group C showed no significant difference 4 weeks after treatment (P>0.05).The LVEF of group C was higher than that of group B 12 weeks after treatment (P<0.05).The incidence rate of adverse reaction of group A and group B were lower than that of group C (P<0.05).Conclusion 160mg/d of valsartan for patients with CHF was found to be able to improve LVEF and heart function and reduce adverse reaction .关键词
慢性心力衰竭/缬沙坦/剂量/心功能Key words
chronic heart failure/valsartan/dose/cardiac function分类
医药卫生引用本文复制引用
陈国英,徐巧玲,余丹..不同剂量缬沙坦治疗慢性心力衰竭的疗效观察[J].健康研究,2015,(1):28-29,32,3.
