健康研究Issue(1)：35-37,3.DOI:10.3969/j.issn.1674-6449.2015.01.014
自然妊娠与 ART 术后妊娠早期流产胎儿的绒毛染色体核型比较分析
A comparative analysis of chromosome karyotype villi of early miscarriage from natural pregnancy and pregnancy by ART
牟春艳 1李苗1
作者信息
- 1. 杭州市余杭区妇幼保健院 产科，浙江 杭州 311000
- 折叠
摘要
Abstract
Objective To understand the chromosome karyotype villi of fetus of miscarriage at early pregnancy both natural and by ART.Method Sample villi from 56 cases of miscarriage at the early stage of pregnancy by ART were taken as the experimental group and sample villi from 51 cases of miscarriage at the early stage of natural pregnancy were taken as the control group of study .Then villi cell culture and chromosome karyotype analysis for both groups were conducted under aseptic condition.Findings Among 56 cases in the experimental group, 52 (92.86%) cases were successful in cell culture;26 (50.00%) cases of unusual karyotypes were found;and 16 (about 46.81%) cases of trisomic karyotype were found.Among the 51 cases in the control group , 47 (92.1%) cases were successful in cell culture;22 (46.81%) cases of unusual karyotypes were found , and 15 ( about 68.18%) cases of trisomic karyotype were identified .The usual karyotype found in women in both groups with less than 2 times of miscarriage was found higher than that in women in both groups with 2 or more times of miscarriage.The difference is statistically significant (P<0.01).Conclusion Miscarriage at the early stage of pregnancy is closely related to fetal chromosomal abnormality .关键词
自然妊娠/辅助生殖技术/自然流产/染色体/核型分析Key words
natural pregnancy/assisted reproductive technology/miscarriage/chromosome/karyotype analysis分类
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牟春艳,李苗..自然妊娠与 ART 术后妊娠早期流产胎儿的绒毛染色体核型比较分析[J].健康研究,2015,(1):35-37,3.
